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Located at 2503 Highway F, Defiance, Missouri 63341, this Single Family Home is for Sale with a price of $825,000 USD. The property was built in 1972, includes 4 bedrooms, has 4 full baths. This listing has 4,534 Sq.Ft. of interior space on a lot of 8 Acres. See all Homes for Sale in Defiance.
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50. 2503 Highway F
1. 2503 Highway F
2. 2503 Highway F
1 of 50
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Listing Details
MissouriDefiance2503 Highway F

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Description

2503 Highway F,

Defiance, MO 63341

A Truly Unique Property Offering Peace, Privacy, & Endless Possibilities! This property has 8+/- acres that is nestled in the heart of nature & a rare find. The expansive 1500+sf original home has been thoughtfully expanded by the current homeowners w/ a 2100+sf addition to create a retreat w/ modern comforts. Over 4,700sf of living space, including a large primary suite w/ private balcony on the 2nd floor, a spacious great room w/ wet bar on main level & a large living/bedroom suite in the basement with its own entrance. This home is perfect for those seeking both serenity & seclusion. Step outside & be embraced by nature, w/a private lake & a surrounding wooded oasis. Just 5 minutes from the charming town of New Melle & 15 minutes from Missouris Wine Country, this home combines peaceful living w/ easy access to local attractions. The walk-out basement offers tremendous flexibility, with two separate entrances making it ideal for multi-generational living or even as a potential income property. In addition there is an impressive 25x28 garage & two-story 25x32 workshop/storage. This loft area offers ample space for hobbies, projects, or storage. This is more than just a home, its a lifestyle. Whether youre seeking a private sanctuary, a multi-use estate, or an investment opportunity, this property is brimming w/ potential. In addition, the home has a BRAND NEW ROOF! put on in June 2025. Tax records show 10 acres. The seller subdivided 1.79 acres off the 10 acres.

This is an Active listing.

Broker Office Phone Number: 636-677-6800

Copyright © 2025MARIS. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

Amenities

  • Carpet
  • Carpeted Floors
  • Dishwasher
  • Fenced
  • Fireplace
  • Refrigerator
  • Tile Flooring
  • Walk-in Closet
  • Wood Floors
  • Dryer Included
  • Ceramic Flooring
  • Washer / Dryer
  • Waterfront
  • Ceiling Fan
  • Asphalt Shingle Roof
  • Driveway
Listing By: Realty Executives Premiere via Data Source: MARIS 
4
Bedrooms
4
Full Baths
$825,000
price
$182
Price Per Sqft
$5,795
Annual taxes
Single Family Home
Property type
1972
Year Built
Francis Howell R-III
School District
Francis Howell R-III
School District
francis-howell-r-iii-school-district-st-charles-mo
Schools
Daniel Boone Elem.
Elementary
Francis Howell Middle
Middle
Francis Howell High
High
13322728
Web Id
25045787
MLS ID
11
Days Posted

Price History

datepricevariancetype
7/4/2025$825,000 6.78 %decreased
2/28/2025$885,000 1.12 %decreased
2/12/2025$895,000 9.14 %decreased
10/11/2024$985,000-Listed
listing agent: Ann Rothweil
more info
4,534 Sq Ft.
interior
8 Acres
Exterior
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    new listing

    2503 Highway F
    Defiance, MO 63341

    $825,000
    4 bd4 ba